性 别:

最高学历、学位:博士

职 称:研究员

个人简介

 浙江大学医学院/附属第一医院双聘研究员,博士生导师。2016年中组部“青年千人计划”入选者。


研究方向

1. 免疫系统在肿瘤的发生、发展过程中的变化及特征;

2. 肿瘤、自身免疫性疾病、重大传染病免疫治疗新途径;

3. gamma delta (gd) T细胞抗原识别及其机制;


成果奖项:(近五年主要成果及奖励情况)


文章:

· Shao Y., Zeng X., Molecular mechanisms of Gut microbiota associated colorectal carcinogenesis. Infect Microb Dis, 2, 96–106 (2020)

· Liu J, Feng B, Xu Y, Zhu J, Feng X, Chen W, Sheng X, Shi X, Pan Q, Yu J, Zeng X, Cao H, Li L,Immunomodulatory effect of mesenchymal stem cells in chemical-induced liver injury: a high-dimensional analysis. Stem Cell Res Ther. 2019 Aug 23;10(1):262.

· Wu P, Zhang T, Liu B, Fei P, Cui L, Qin R, Zhu H, Yao D, Martinez RJ, Hu W, An C, Zhang Y, Liu J, Shi J, Fan J, Yin W, Sun J, Zhou C, Zeng X, Xu C, Wang J, Evavold BD, Zhu C, Chen W, Lou J. Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition. Mol Cell, 2019 7;73(5):1015-27.

· Fang W, Zhai X, Han D, Xiong X, Wang T, Zeng X, He S, Liu R, Miyata M, Xu B, Zhao H. CCR2-dependent monocytes/macrophages exacerbate acute brain injury but promote functional recovery after ischemic stroke in mice. Theranostics, 2018 ,8(13):3530-3543

· Huang J, Zeng X, Sigal N, Lund PJ, Su LF, Huang H, Chien YH, Davis MM. Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer. Proc Natl Acad Sci U S A, 2016, 113, E1890-7